Pure Encapsulaitons Vitamin D3 & K2

Supports bone and vascular health‡

• The blend of Vitamin D3 and K2 provide augmented support for bone + vascular health‡
• Promotes healthy calcium utilization to maintain bone health‡
• Vitamin D3 helps support bone health by enhancing the intestinal absorption of calcium‡
• Vitamin K2 is key in maintaining calcium balance within bone and vascular tissues‡

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Product Information

• Helps maintain calcium balance in vascular tissue to support healthy arterial blood flow and vascular elasticity‡
• Provides vitamin D3 and vitamin K2 in one convenient capsule
• Made with hypoallergenic ingredients
• Vitamin K2 (MK-7) is derived from flower extracts geraniol and farnesol
• Vitamin D3 is derived from lanolin

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How to use: Take 1 capsule daily, with a meal or as directed by a health professional.

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Science & Research

Vitamin K2 (menaquinone-7) is a fat-soluble nutrient with an important role in maintaining arterial calcium balance and vascular elasticity.(1-12) In a systematic review involving five studies, higher intakes of vitamin K2 were associated with cardiovascular health.(10) In an observational study involving 564 postmenopausal women, higher intake of vitamin K2 was associated with calcium balance in the vascular tissue.(8) One of the primary functions of vitamin K2 is to support the carboxylation of matrix Gla-protein (MGP), a key protein involved in calcium balance.(11) Accordingly, several studies indicate that Vitamin K2 also supports proper utilization of calcium in bone. Clinical research indicates that obtaining adequate amounts helps to maintain bone health.(1-6) Vitamin K2 and vitamin D3 both participate in the regulation of osteocalcin, a biomarker of bone formation.‡

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‡ These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The content on this website is for educational and general wellness information purposes only and should not be considered to be medical advice. It is not intended to replace the advice of a healthcare professional. Please consult with a healthcare professional with any questions about the appropriate supplements for you.

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References

(1) Gropper SAS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th Ed. Chapter 10, pp. 412-414. Wadsworth/Cengage Learning, Australia. c.2009.
(2) El Borolossy R, El-Farsy MS. Eur J Clin Nutr. 2022 Jun;76(6):848-854.
(3) Qiu C, Zheng H, Tao H, et al. Mol Cell Biochem. 2017 Sep;433(1-2):149-159.
(4) Yamaguchi M, Sugimoto E, Hachiya S. Mol Cell Biochem. 2001 Jul;223(1-2):131-7.
(5) Zhang Y, Liu Z, Duan L, et al. Calcif Tissue Int. 2020 May;106(5):476-485.
(6) Knapen MH, Drummen NE, Smit E, et al. Osteoporos Int. 2013 Sep;24(9):2499-507.
(7) Knapen MH, Braam LA, Drummen NE, et al. Thromb Haemost. 2015 May;113(5):1135-44.
(8) Beulens JW, Bots ML, Atsma F, et al. Atherosclerosis. 2009 Apr;203(2):489-93.
(9) Mansour AG, Hariri E, Daaboul Y, et al. J Am Soc Hypertens. 2017 Sep;11(9):589-597.
(10) Rees K, Guraewal S, Wong YL, et al. Maturitas. 2010 Oct;67(2):121-8.
(11) Dalmeijer GW, van der Schouw YT, Magdeleyns E. Atherosclerosis. 2012 Dec;225(2):397-402.
(12) Vermeer C and Vik H. Vascul Dis Ther. 2020;5: doi: 10.15761/VDT.1000179.
(13) Gigante A, Brugè F, Cecconi S, et al. J Tissue Eng Regen Med. 2015 Jun;9(6):691-701.